Nanoparticles to treat dry eye syndrome
Dry eye syndrome is commonly treated by applying drops several times a day. Canadian researchers have now developed a topical solution containing nanoparticles that provides the eye with moisture for several days. Their study was presented in “Nano Research”.
Scientists at the University of Waterloo infused biocompatible nanoparticles with Cyclosporine A, the drug also found in eye drops. They made the nanoparticles stick to the eyeball for longer periods of time and progressively deliver the right dose of the drug. After five days, they are absorbed by the body.
Due to the fact that the particles stay on the eye and are not washed out like normal eye drops on account of the eye’s ability to self-cleanse, only a fraction of the drug – five per cent – compared to eye drops, are required. This also prevents irritation and reduces the risk of toxic exposure due to excessive use of eye drops, says study leader Shengyan Liu. Clinical trials using the nanoparticles are planned.
There are many other ways to help with dry eyes. Lubricant eye drops are the mainstay of dry eye therapy – however there are many other ways to improve comfort.
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